Cryptotanshinone翻译
WebCryptotanshinone can also inhibit alcoholic liver disease by blocking hepatic cell death and fatty acid synthesis (Yin et al., 2009). Salvianolic acid B, isolated from S. miltiorrhiza , … WebMar 10, 2024 · Cryptotanshinone (CTS) is a lipophilic constituent of Salvia miltiorrhiza, with a broad-spectrum anticancer activity. We have observed that CTS enhances the efficacy of gefitinib in human lung cancer H1975 cells, yet little is known about its molecular mechanism. To explore how CTS enhances H1975 cell sensitivity to gefitinib, we figured …
Cryptotanshinone翻译
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WebAug 26, 2024 · 一,主要化学成分,结构与性质. 丹参含有脂溶性成分和水溶性成分两大部分.脂溶性成分大多为共轭醌,酮类化合物,具有特征的橙黄和橙红色.如丹参酮I,丹参酮IIA,丹参酮IIB,隐丹参酮等.水溶性成分有丹参素,丹参酸甲,乙,丙,原儿茶酸,原儿茶醛等. 丹参酮I (Tanshinone I ... WebThe nature of intestinal absorption of most herbal medicine is unknown. Cryptotanshinone (CTS) is the principal active constituent of the widely used cardiovascular herb Salvia miltiorrhiza (Danshen). We investigated the oral bioavailability of CTS in rats and the mechanism for its intestinal absorption using several in vitro and in vivo models: 1) Caco …
WebProvided are a composition for stimulating differentiation of MSCs into osteoblasts, which includes cryptotanshinone, and an osteogenesis stimulator including cryptotanshinone and MSCs. When the cryptotanshinone is treated to the MSCs, the differentiation into osteoblasts is stimulated, and thus osteogenesis of a patient may be stimulated by … WebCryptotanshinone is a STAT3 inhibitor with IC50 of 4.6 μM in a cell-free assay, strongly inhibits phosphorylation of STAT3 Tyr705, with a small effect on STAT3 Ser727, but none against STAT1 nor STAT5. Cryptotanshinone …
WebMar 2, 2024 · Cryptotanshinone (CPT), as a major component of Salvia miltiorrhiza Bunge (Danshen), displays many pharmacological activities including anti-inflammatory effects. However, the exact cellular and molecular mechanisms of the anti-inflammatory activities of CPT remain to be elucidated. The present study was aimed to clarify its mechanisms on … Web目的:观察丹参酮对冠心病心绞痛(心血淤阻型)患者的疗效并做初步评价,并对其机制做初步探究。方法:选取符合纳入标准的冠心病稳定型心绞痛(心血瘀阻型)患者60人,随机分为两组,治疗组30人,对照组30人。入院时常规检查,记录患者心电图改变程度及所需生化指标,记录患者临床症状。两 ...
WebCryptotanshinone is a quinoid diterpene isolated from the root of the Asian medicinal plant, Salvia miotiorrhiza bunge. Recently it was discovered that the compound is a potent …
Web2.4 Antitumor. Tanshinone IIA, cryptotanshinone and tanshinone I are the main antitumor ingredients of Salvia miltiorrhiza. The antitumor mechanisms of tanshinone IIA are as follows: (1) inhibiting the growth and proliferation of cancer cells, (2) inducing apoptosis, (3) inducing cell cycle arrest, and (4) inhibiting the invasion, migration and ... dangers of microwaves wavesWebDihydrotanshinone C18H14O3 CID 5316743 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities ... birmingham townhomes for saleWeb目的观察丹参二萜醌类活性成分对胰腺癌的抑制效应,探讨其诱导胰腺癌凋亡的作用机制。方法胰腺癌细胞AsPC-1、BxPC-3用含10%gibco胎牛血清的RPMI1640培养液培养,按隐丹参酮组(30μM)、丹参新酮组(15μM)、去氢丹参新酮组(15μM)分别加药处理。Cell … birmingham townhomes st paul mnWebMay 20, 2024 · The results showed that cryptotanshinone could reduce the tumor mass, increase the tumor suppression rate, and enhance the chemotherapeutic effect of 5-fluorouracil by a mechanism related to inhibition of the Janus kinase 2/signal transducer and activator of transcription 3 signaling pathway. Expand. View 1 excerpt, cites background; birmingham township pa websiteWebJan 4, 2024 · Cryptotanshinone administration significantly reduces the body weight and food intake of ob/ob mice (C57BL/6J-Lepob) and diet-induced obese (DIO) mice in a dose-dependent manner. Cryptotanshinone causes noticeably less fat in the adipose tissues, significant reductions of serum triglycerides and cholesterol levels, and 2.5- to 3-fold … dangers of milk thistleWebMar 2, 2024 · Cryptotanshinone (CPT), as a major component of Salvia miltiorrhiza Bunge (Danshen), displays many pharmacological activities including anti-inflammatory effects. … dangers of mining in the 1800sWebAug 13, 2024 · Results: The combination of fosfomycin and cryptotanshinone had a synergistic effect on most (71.43%) of the FRSA and had a partial (28.57%) synergistic effect on a small part. In addition, time sterilization curve verified synergistic activity between cryptanshinone and fosfomycin against FSSA and FRSA, especially when fosfomycin was … birmingham town house