Line-1 orf1p antibody
NettetLINE-1 ORF1p is a component of apoptotic blebs and a substrate for GrB. Anti-ORF1p antibodies are enriched in SLE subjects but are not associated with dynamic markers of … NettetAnti-mouse LINE-1 ORF1p rabbit polyclonal antibodies. This fantastic reagent was developed and characterized by Sandy Martin in 1991. As the piRNA field took off in 2006, this polyclonal antibody has become very popular following our first description of Maelstrom knockout male mice.
Line-1 orf1p antibody
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NettetLINE-1 ORF1p Antibodies available through Novus Biologicals. Browse our LINE-1 ORF1p Antibodies all backed by our Guarantee+. NettetBackground: LINE-1 ORF-1p is encoded by the human pro-oncogene LINE-1. Our previous work showed that LINE-1 ORF-1p could enhance the resistance of hepatocellular carcinoma (HCC) cells to antitumor agents. However, the mechanisms involved in LINE-1 ORF-1p-mediated drug resistance remain largely unknown.
NettetL1/ORF2 Antibody is directed against two regions within the endonuclease domain of L1 ORF2 protein. Reactivity occurs against human L1/ORF2 protein and is useful in … Nettet3. jan. 2024 · ORF1p, a nucleic acid chaperone that binds LINE-1 mRNA, was predominantly expressed in the cytoplasm, with minor localization in the nucleus. ORF2p, containing endonuclease and reverse transcriptase domains, exhibited punctate foci in the nucleus and also displayed co-localization with PCNA and γH2AX.
NettetThis product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free … NettetImmunofluorescent analysis of 4% paraformaldehyde-fixed, 0.1% Triton X-100 permeabilized MCF7 (human breast adenocarcinoma cell line) cells labeling LINE-1 …
Nettet12. apr. 2024 · Decades ago, the oncology community took on the crucial challenge of detecting cancer at the earliest possible stage. Overall, survival rates improve dramatically...
Nettet27. jan. 2024 · This study generated new LINE-1 ORF1p peptide antibodies. References Zheng, L. et al. Incidence and mortality of ovarian cancer at the global, regional, and … grbx stock forecastNettet9. feb. 2024 · LINE-1 ORF1p expression has been observed in around 47% of tumors tested, and roughly in 40% of prostate tumors . In some cancers, such as pancreatic … chondroclast cellsNettetLINE1-ORF 1P is a nucleic acid-binding protein which is essential for retrotransposition of LINE-1 elements in the genome. It is also reported to function as a nucleic acid … grb wisconsinNettet29. des. 2024 · These studies demonstrated expression and sub-cellular localization of LINE-1 proteins, ORF1p, with antibody 4H1, and ORF2p, with antibody chA1-L1. Results Here we conduct immunoprecipitation/mass spectrometry analysis using chA1-L1 antibody against ORF2p in LNCaP cells. chondroclast definitionNettet10. nov. 2024 · “Across most major carcinoma types in our initial study, the rates of finding overexpression in LINE-1 transposon were between 50 and 95 percent or higher.” A family of transposons known as long interspersed nuclear element 1 (LINE-1), including the open reading frame 1 protein (ORF1p), appear in many forms of cancer—possibly even … grc01-by-02aNettetAnti-LINE-1 ORF1p Antibody, clone 4H1 Detect LINE-1 retrotransposable element ORF1 protein using this mouse monoclonal Anti-LINE-1 ORF1p Anibody, clone 4H1, Cat. No. … grc-20-90-t2h5-d-a1chondrococcus