The meaning of notch
SpletIn mechanical engineering and materials science, a notch refers to a V-shaped, U-shaped, or semi-circular defect deliberately introduced into a planar material. In structural … SpletIn considering Notch-1 receptor as a potential target, we performed immunohistochemistry on tissue microarrays to determine 1) whether the receptor is overexpressed in tumor cells as compared to their corresponding normal tissues and 2) the clinical significance of its expression levels in human breast, colorectal, lung and prostate cancers.
The meaning of notch
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Spletnotching In English, many past and present participles of verbs can be used as adjectives. Some of these examples may show the adjective use. Similarly, notching can precede … Spletnotch 1. noun, informal A relative degree, level, or step. You need to bring up this branch's productivity several notches if you want to keep your job. While their newest phone is a …
SpletA notch is a small cut or nick in something. People make notches to keep track of things. If you've even seen a little U-shaped or V-shaped cut in something, you've seen a notch. In … Spletnotch (n): 1. An indentation or incision on an edge or surface. 1.2 A nick made on something in order to keep a score or record. 1.3 A point or degree in a scale. notch (v): 1. Make …
SpletNotch signaling, which was initially identified in Drosophila wing morphogenesis, plays pivotal roles in cell development and differentiation. Optimal Notch pathway activity is essential for normal development and dysregulation of Notch signaling leads to various human diseases, including many types of cancers. In hematopoietic cancers, such as T … SpletThe Spartans turned it up a notch in the second half. 2 a V-shaped cut or hole in a surface or edge Cut a notch near one end of the stick. 3 American English a passage between two mountains or hills → top-notch Examples from the Corpus notch • Grover loosened his belt a notch. • He raised his chin a notch and swiveled his head at Earl ...
Splet16. nov. 2024 · Meaning ‘Take it up a notch’ is a common figurative saying in the English language that is usually used to mean that something or someone should (or is going to) increase their performance or capacity. When someone ‘takes it up a notch’ then it is implied that their intensity or dedication to the task at hand is going to (or has) increased.
Spletnotch 1. noun, informal A relative degree, level, or step. You need to bring up this branch's productivity several notches if you want to keep your job. While their newest phone is a notch above their previous model, not enough has improved to warrant its hefty price tag. 2. verb, informal To score, secure, or achieve (something). raleigh enduranceSpletWhat's the origin of the phrase 'Top notch'? 'Top notch' is of American origin and followed on from the earlier, British 'topping'. The US also later adopted 'the tops'. All these phrases mean the same thing. Presumably, those who were 'top notch' had avoided the indignity of being ' taken down a peg '. The earliest example I've found of 'top ... ovation staffing houstonSplet: of the highest quality : first-rate a top-notch work topnotcher ˈtäp-ˈnä-chər noun Synonyms A-OK A1 awesome bang-up banner beautiful blue-chip blue-ribbon boffo bonny [ chiefly … raleigh endocrinology physiciansSpletnotch noun [C] (CUT) a cut in a hard surface: The rope had jammed in a V-shaped notch. notch noun [C] (POSITION) an imaginary point or position in a comparison of amounts or … top-notch definition: 1. excellent: 2. excellent: 3. excellent; of very good … notch meaning: 1. a V-shaped cut in a hard surface: 2. a hole or mark on the edge of … raleigh endoscopy center mainSpletNotch signaling, which was initially identified in Drosophila wing morphogenesis, plays pivotal roles in cell development and differentiation. Optimal Notch pathway activity is … ovation standard elite 2778 ax reviewSplet07. dec. 2024 · Meaning "to place in a notch, to fit (an arrow) to the string by the notch" is from 1630s. Meaning "to mark or score" (1837) is sporting slang, originally in cricket, … raleigh endoscopy mainSpletNoun Opposite of a nick made on something in order to keep a score or record closing closure blockage obstruction occlusion impasse solid barrier barricade juncture blocking Noun Opposite of a deep narrow valley or gorge in the earth's surface worn by running water plain Noun Opposite of a long, narrow cut or depression in a hard material ovation standard c2079ax-5